I have always liked the mindset that the base coaches are stop signs, not go signs.Biggest thing by far is getting that runner going into 2b, to be looking at 3b coach early enough to get the keep coming or stop sign.
Now, I understand that how you actually run the bases varies by situation. I don't want you taking a curved route to first if we're trying to beat a force out. But if you're thinking score as soon as you leave the box, you only have one sign/decision to make and that's stop.
It's not infallible because defenses will do weird things sometimes, but I found more often than not, if they weren't already going when I said go, it was too late. 10U will have a higher margin for error, but you're building for the long term.